• Users Online: 700
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 

 Table of Contents  
Year : 2018  |  Volume : 53  |  Issue : 1  |  Page : 38-43

Opening wedge high tibial osteotomy in varus osteoarthritis of the knee without bone graft

Department of Orthopeadic Surgery, Zagazig University, Zagazig, Egypt

Date of Submission13-May-2018
Date of Acceptance05-Jun-2018
Date of Web Publication02-Jan-2019

Correspondence Address:
Mohamed E Attia
Department of Orthopeadic Surgery, Zagazig, University, Zagazig
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/eoj.eoj_15_18

Rights and Permissions

Background The aim of this study was to evaluate the efficacy and short-term results of medial opening wedge high tibial osteotomy with the use of a wedge toothed plate in patients with medial compartment osteoarthrosis.
Patients and methods This study was conducted from April 2010 and September 2012 and included 16 knees of seven female patients and nine male patients. Their average age was 40 years (range: 28–52 years), and they were treated with medial opening wedge high tibial osteotomy for varus knees with early medial compartment osteoarthrosis. The osteotomy sites were fixed with a wedge toothed plate without bone graft. The mean follow-up period was 11.4 months (range: 6–15 months).
Results The average union time was 15 weeks (range: 8–24 weeks). The mean preoperative and postoperative Lysholm scores were 54.1 (range: 30–60) and 82 (range: 67–95), respectively. The mean preoperative femorotibial angle was 3.5° in varus malalignment (range: 3° valgus to 9° varus). It was 7.3° valgus postoperatively. The mean correction of the mechanical axis was 10.7°. There was loss of correction in one patient and needed revision. Four (25%) cases had delayed union.
Conclusion Medial opening wedge osteotomy with the use of a wedge toothed plate had advantages of easy application and maintenance of correction in the early follow-up period without bone graft application. Consolidation is obtained without interfering with the rehabilitation period.

Keywords: bone graft, knee, opening wedge, varus

How to cite this article:
Attia ME. Opening wedge high tibial osteotomy in varus osteoarthritis of the knee without bone graft. Egypt Orthop J 2018;53:38-43

How to cite this URL:
Attia ME. Opening wedge high tibial osteotomy in varus osteoarthritis of the knee without bone graft. Egypt Orthop J [serial online] 2018 [cited 2019 Oct 15];53:38-43. Available from: http://www.eoj.eg.net/text.asp?2018/53/1/38/249272

  Introduction Top

Opening wedge high tibial osteotomy (HTO) is a reasonable treatment for unicompartmental medial osteoarthritis with varus deformity in young, active patients [1],[2],[3]. It improve transfer of a weight-bearing load from an affected medial compartment to lateral compartment of the knee, relieves symptoms, increases healing of damaged cartilage [4], and slows the progression of arthrosis in a knee with varus alignment [5],[6]. Overcorrection and undercorrection of the deformity have poor clinical results [6],[7],[8], and it is important to achieve and maintain accurate correction of limb alignment until complete healing. The causes of loss of fixation are owing to lack of fixation and instability [8],[9],[10]. Optimal corrections was defined to be 8° of anatomic valgus [11], between 3° and 6° of mechanical valgus [3], when the weight-bearing line (WBL) passed through a point between 62 and 66% [12], or 62.5% [6],[13] of the tibial plateau width. Introduction of the plate fixator for HTO [14], the open-wedge technique, became more secure owing to higher stability of the osteosynthesis [15],[16]. Many surgical techniques have been described since the first description by Jackson [17], such as dome osteotomy [17],[18], medial opening wedge [19], lateral closure wedge [20], and Ilizarov [21]. Medial opening wedge HTO above the tubercle had few complications [22],[23], in comparison with other methods, and is seen as a correction technique of greater precision [3]. Its advantages include the following: (i) lack of need for lateral dissection and/or osteotomy of the fibula, thereby diminishing the risk of praxis of the common fibular nerve; (ii) provision of limb stretching, given that in arthrosis there is diminution of the joint space, with relative shortening; (iii) the results from angular correction are superior to those from using a lateral closure wedge; and (iv) provision of proximal tibial correction that is more anatomical.

  Patients and methods Top

Sixteen patients were treated by medial opening wedge high osteotomy fixed with wedge toothed plate the for treatment of genu varus deformity and pain owing to osteoarthritis of medial compartment of the knee or varus deformity causing chronic ligament instability of knee between April 2010 and September 2012 at Zagazig University Hospital and Health Insurance Hospital. Nine patients were men and seven were women. The age ranged from 28 to 52 years. The mean follow-up period was 11.4 months (range: 6–15 months) ([Table 1]). Patient selections with varus malalignment symptoms with overloading in the medial compartment of the knee from osteoarthritis or knee instability due to chronic ligaments injury. Varus malalignment was considered when the tibiofemeoral mechanical axis passed through the medial tibial plateau or when the tibiofemoral mechanical angle was more than 3° compared with the opposite side. The range of motion of the knee joint had to be at least 100° from full extension and to flexion. Patients older than 60 years, adolescents with radiological open growth plates or infection of the knee joint, varus malalignment more than 15°, flexion deformity more than 15°, and grade III Ahlback were excluded. The radiological documentation included standard knee radiographs, a weight-bearing anteroposterior view, and a lateral view. The WBL was found by drawing a line from the centre of the femoral head to the centre of the ankle mortise. The horizontal distance from the WBL to the medial edge of the tibial plateau was then divided by the width of the tibial plateau. Thus, a WBL ratio of less than 0.5 indicated varus angulation with the load shifted medially, whereas a value of greater than 0.5 denoted valgus angulations with the load shifted toward the lateral compartment. The osteotomy opening size ranged from 8 to 14 mm in an attempt to shift the mechanical axis to the Fujisawa point (62% of the tibial plateau located on the lateral side) [6].
Table 1 Patient’s data and results

Click here to view

Surgical technique

Arthroscopy was performed before HTO to treat meniscal and chondral lesions.

Skin incision started distal to the joint line and ends 4–5 cmcm distal to the tibial tuberosity. The superficial medial ligament is subperiosteally elevated and retracted around the posterior edge of the tibia. A guide wire is passed from the medial tibial cortex starting from a point that usually corresponds to a bow in the proximal tibia aiming at the lateral tibial cortex at the level of tip of the fibular head. In knees with short proximal fragment for fixation (short distance between the joint line and tibial tuberosity), the anterior third of the cut can be modified to be more slanting to pass proximal to the tibial tuberosity. Opening of the osteotomy was done without force with the aid of bone spreader to avoid fracture of the lateral tibial plateau. All osteotomies were done without bone graft or bone substitutes. Internal fixation was done using four-holes toothed plate that offers osteotomy opening sizes of 8, 10, 12, and 14 mm ([Table 2]). Wound closure was done without a suction drain with anatomical closure of the pes anserinus and soft tissues to preserve the fracture haematoma in the osteotomy gap. Lateral cortical fracture is a severe complication that can occur during the surgery, decreasing axial resistance (47%) and rotational resistance (54%) of the osteotomy [24]. It occurs when the lateral tibial cortex is perforated or cut by the chisel. This complication occurs when opening the osteotomy wedge with the anterior and posterior cortex intact, which is detected by subluxation of the osteotomy. If it occurs, it is necessary to add a lateral fixation (screw or hook) at the apex of the opening wedge, to increase the stability of the osteotomy [25].
Table 2 Osteotomy opening size and number of patients

Click here to view


Patients were kept nonweight bearing with mobilization in bed till removal of stitches to decrease the postoperative oedema and enhance good soft tissue healing. Low-molecular-weight heparin was given in high-risk patients as prophylaxis against deep venous thrombosis. Partial weight bearing with crutches was allowed. Isometric quadriceps and active ankle exercises were begun immediately after surgery. Active exercises, patellar mobilization, and straight-leg raises were started on the first postoperative day. Partial weight-bearing was allowed at 6 weeks, and full weight-bearing at eight to 12 weeks postoperatively. Patients were reviewed monthly for clinical and radiologic assessments till union and then at 6 months. Repeated radiographs were assessd for bone union as mature trabecular continuity observed in both the anteroposterior and the lateral radiographs. Clinical assessment was performed using Lysholm score and recorded results at 6 months and at the last follow-up ([Figure 1]).
Figure 1 (a) Standing full-length lower limb radiograph. (b) Short film nonweight bearing radiographic knee. (c) Postoperative radiograph with opening wedge osteotomy without graft. (d–f) Follow-up with progress healing.

Click here to view

Statistical analysis

The following statistical methods were used for analysis of results of the present study. Data were checked, entered, and analyzed using SPSS, version 19 (SPSS Inc., Chicago, Illinois, USA) in Windows 7 for data processing and statistic.

The statistical analysis is illustrated in [Figure 2] and [Table 3],[Table 4],[Table 5],[Table 6],[Table 7],[Table 8],[Table 9].
Figure 2 Different wedge sizes in studied group.

Click here to view
Table 3 Association between mean ages and wedge size

Click here to view
Table 4 Association between sex and wedge size

Click here to view
Table 5 Association between pathology and wedge size

Click here to view
Table 6 Association between mean union time/weeks and wedge size

Click here to view
Table 7 Association between mean follow-up/ms and wedge size

Click here to view
Table 8 Association between complication and wedge size

Click here to view
Table 9 Association between results and wedge size

Click here to view

  Results Top

Radiological results

Sixteen patients underwent open wedge medial HTO in this study which united in all patients. Four patients had a delay in union, which resolved by 6–8 months, postoperatively. A loss of fixation occurred in one patient owing to early full weight bearing postoperatively and needed revision, which was considered as failure. There was significant difference between the healing time and the size of the osteotomy opening. There were no infections, loss of knee motion, and nerve or arterial injuries. Full weight bearing was achieved at a mean of 9 weeks (range: 5–12 weeks), postoperatively. Seven (43.8%) knees had osteotomy openings of 10 mm or less, and nine (56.25%) knees had more than 10 mm osteotomy openings. The osteotomy united in all patients at the end of follow-up. Average time to union was 15 weeks (range: 8–24 weeks). By the end of the third month (12 weeks), 62.5% of osteotomies have healed.

Clinical results

Patients were evaluated with Lysholm score at 6, 12, and 24 months postoperatively, and the mean preoperative and postoperative Lysholm scores were 54.1 (range: 30–60) and 82 (range: 67–95), respectively. Postoperative radiological follow-up after 6 weeks, 6 months, and 12 months with good quality radiograph. The mean preoperative femorotibial angle was 3.5° in varus malalignment (range: 3° valgus to 9° varus). It was 7.3° valgus, postoperatively. The mean correction of the mechanical axis was 10.7°, with loss of correction during the follow-up period in one patient and needed revision. Four (25%) cases had delayed union. The lateral cortex was not broken in any patient. All patients were satisfied with the treatment except one patient who needed revision.

  Discussion Top

Opening wedge HTO has become popular in recent years because it enables a medial approach, which minimizes the risks of neurovascular lesion and the need for dissection of the soft tissues. It enables the wedge to be opened and closed during the procedure, giving a better end result. Another advantage of this technique is that it enables earlier mobility and immediate weight-bearing, depending on the implant used [26]. Open wedge osteotomy of the medial metaphyseal tibia does not compromise limb length. It enables correction of medial ligamentous laxity and operation on the diseased compartment enabling correction of up to 15° of deformity, but it is less stable than closed wedge osteotomy. Thus, fragment fixation is of critical importance. The procedure is indicated for limbs with a good healthy vascular status, excellent triceps strength, osteoarthritis limited to a single medial compartment, and pain/disability affecting the quality of life. An unstable knee (lateral tibial subluxation of >1 cm) with a narrow medial joint space and/or bone loss (2–3 mm), knee flexion contracture (>15°), limited knee flexion (<90°), major knee deformities (>15°) and associated inflammatory arthropathies are contraindications for open wedge osteotomy. Excellent and good results were achieved in 67.5% of patients. Thirty-seven (86.0%) patients reported clinical improvement at 24 months compared with preoperative status. Evaluation of the clinical course following HTO revealed a significant increase in function after 12 and 24, but not at 6 months after surgery. A further increase was found between 12 and 24 months; 67.5% of the study population returned to their predisease sports activity level at 24 months after surgery. Except for one case of intra-articular fracture, no severe intraoperative complications were found. One case of nonunion that demanded additional surgery was observed [27]. In this study, excellent\good results were seen in 93.7%, failure in one (6.3%) patient, and union was delayed in four (25%) patients at the end of follow-up period. The Puddu et al. [28] plate was developed as a simple fixation device for the opening-wedge osteotomy and uses two screws proximally and two screws distally. Amendola et al. [29] reported on their first 74 consecutive patients over a 2-year period. Their results indicate a 90% satisfaction compared with the 93.8% satisfaction rate in this study. All osteotomies in this series were held by the toothed angled plate plate, with two holes above and below the osteotomy. Intra-articular fracture as an extension of the osteotomy associated with a high osteotomy and too thick an osteotome, and this complication was avoided in comparison with this study by using thin osteotome large-sized proximal fragment. Four failures of fixation were reported compared with one case occurred in this study owing to early weight bearing and loss of fixation and need revision. These failures were attributed to early, aggressive weight bearing. The average decrease in the Blackburne–Peel ratio of patella height was 0.17, with two patients developing patella infera, but no correlation with the functional result was found. In this study, four (25%) cases had delayed union, which was treated by prolonged immobilization, whereas one case needed revision after loss of fixation and was considered as failure, and no cases of fracture, nonunion, or peroneal nerve palsy were observed.Patella baja is a recognized complication of opening-wedge osteotomy [30], associated with immobilization following osteotomy. The complication is reduced if early mobilization is allowed, preventing tethering of the patella. Opening wedge HTO can be performed without grafting, and early weight-bearing can occur without an elevated risk of nonunion or loss of secondary correction. Functional results showed that 92% of the patients were satisfied or very satisfied with the procedure. High level of good results were expected in the first 5 years after a medial high tibial opening wedge osteotomy [31],[32],[33],[34],[35],[36].

  Conclusion Top

A medial opening wedge HTO without grafting can be stabilized with a locking plate and can be used to treat medial tibiofemoral knee osteoarthritis in an active individual with genu varum. The reliability of the plate allows for a simpler postoperative recovery with early weight-bearing and primary union, which gets away from the risks related to filling the osteotomy site with bone or an inert substitute. The instrumentation to control the angle of correction must be used carefully to attain the desired angular correction. Conversely, spontaneous and total filling of the osteotomy site is usually achieved with this technique. Despite the routine addition of bone graft as a part of the HTO procedure, this study supports medial opening-wedge HTO without bone graft or bone substitutes, which shortens the operative time and avoids unnecessary donor site morbidity.

Financial support and sponsorship


Conflicts of interest

There are no conflicts of interest.

  References Top

Coventry MB, Ilstrup DM, Wallrichs SL. Proximal tibial osteotomy. A critical long-term study of eighty-seven cases. J Bone Joint Surg Am 1993; 75:196–201.  Back to cited text no. 1
Insall JN, Joseph DM, Msika C. High tibial osteotomy for varus gonarthrosis. A long-term follow-up study. J Bone Joint Surg Am 1984; 66:1040–1048.  Back to cited text no. 2
Hernigou P, Medevielle D, Debeyre J, Goutallier D. Proximal tibial osteotomy for osteoarthritis with varus deformity. A ten to thirteen-year follow-up study. J Bone Joint Surg Am 1987; 69:332–354.  Back to cited text no. 3
Matsunaga D, Akizuki S, Takizawa T, Yamazaki I, Kuraishi J. Repair of articular cartilage and clinical outcome after osteotomy with microfracture or abrasion arthroplasty for medial gonarthrosis. Knee 2007; 14:465–471.  Back to cited text no. 4
Ivarsson I, Myrnerts R, Gillquist J. High tibial osteotomy for medial osteoarthritis of the knee. A 5 to 7 and 11 year follow-up.J Bone Joint Surg Br 1990; 72:238–244.  Back to cited text no. 5
Fujisawa Y, Masuhara K, Shiomi S. The effect of high tibial osteotomy on osteoarthritis of the knee. An arthroscopic study of 54 knee joints. Orthop Clin North Am 1979; 10:585–608.  Back to cited text no. 6
Odenbring S, Egund N, Hagstedt B, Larsson J, Lindstrand A, Toksvig-Larsen S. Ten-year results of tibial osteotomy for medial gonarthrosis. The influence of overcorrection. Arch Orthop Trauma Surg 1991; 110:103–108.  Back to cited text no. 7
Pape D, Adam F, Rupp S, Seil R, Kohn D. Stability, bone healing and loss of correction after valgus realignment of the tibial head. A roentgen stereometry analysis [in German]. Orthopade 2004; 33:208–217.  Back to cited text no. 8
Sprenger TR, Doerzbacher JF. Tibial osteotomy for the treatment of varus gonarthrosis. Survival and failure analysis to twenty-two years. J Bone Joint Surg Am 2003; 85:469–474.  Back to cited text no. 9
Miniaci A, Ballmer FT, Ballmer PM, Jakob RP. Proximal tibial osteotomy. A new fixation device. Clin Orthop Relat Res 1989; 246:250–259.  Back to cited text no. 10
Coventry MB. Upper tibial osteotomy for osteoarthritis. J Bone Joint Surg Am 1985; 67:1136–1140.  Back to cited text no. 11
Dugdale TW, Noyes FR, Styer D. Preoperative planning for high tibial osteotomy. The effect of lateral tibiofemoral separation and tibiofemoral length. Clin Orthop Relat Res 1992; 274:248–264.  Back to cited text no. 12
Noyes FR, Barber SD, Simon R. High tibial osteotomy and ligament reconstruction in varus angulated, anterior cruciate ligament-deficient knees. A two- to seven-year follow-up study. Am J Sports Med 1993; 21:2–12.  Back to cited text no. 13
Staubli AE, De Simoni C, Babst R, Lobenhoffer P. TomoFix: a new LCP-concept for open wedge osteotomy of the medial proximal tibia − early results in 92 cases. Injury 2003; 34(Suppl 2):B55–B62.  Back to cited text no. 14
Agneskirchner JD, Freiling D, Hurschler C, Lobenhoffer P. Primary stability of four different implants for opening wedge high tibial osteotomy [published online ahead of print November 12, 2005]. Knee Surg Sports Traumatol Arthrosc 2006; 14:291–300.  Back to cited text no. 15
Brinkman JM, Lobenhoffer P, Agneskirchner JD, Staubli AE, Wymenga AB, van Heerwaarden RJ. Osteotomies around the knee: patient selection, stability of fixation and bone healing in high tibial osteotomies. J Bone Joint Surg Br 2008; 90:1548–1557.  Back to cited text no. 16
Jackson J. Osteotomy for osteoarthritis of the knee. Proceedings of the Sheffield Regional Orthopaedic Club. J Bone Joint Surg Br 1958; 40: 826.  Back to cited text no. 17
Takahashi T, Wada Y, Tanaka M, Iwagawa M, Ikeuchi M, Hirose D. Domeshaped proximal tibia osteotomy using percutaneous drilling for osteoarthritis of the knee. Arch Orthop Trauma Surg 2000; 120:32–37.  Back to cited text no. 18
Spahn G. Complications in high tibial (medial opening wedge) osteotomy. Arch Orthop Trauma Surg 2003; 124:649–653.  Back to cited text no. 19
Catagni M, Guerreschi F, Ahmad T, Cattaneo R. Treatment of genu varum in medial compartment osteoarthritis of the knee using the Ilizarov method. Orthop Clin North Am 1994; 25:509–514.  Back to cited text no. 20
Conventry M. Osteotomy of the upper portion of the tibia for degenerative arthritis of the knee. Apreliminary report. J Bone Joint Surg Am 1965; 47:984–990.  Back to cited text no. 21
Koshino T, Murase T, Saito T. Medial opening-wedge high tibial osteotomy with use of porous hydroxyapatite to treat medial compartment osteoarthritis of the knee. J Bone Joint Surg Am 2003; 85:78–85.  Back to cited text no. 22
Warden SJ, Morris HG, Crossley KM, Brukner PD, Bennell KL. Delayed- and non-union following opening wedge high tibial osteotomy: surgeons’ results from 182 completed cases. Knee Surg Sports Tramatol Arthosc 2005; 13:34–37.  Back to cited text no. 23
Puddu G, Franco V. Femoral antivalgus opening wedge osteotomy. Oper Tech Sports Med 2000; 8:1.  Back to cited text no. 24
Paccola CA, Fogagnolo F. Open-wedge high tibial osteotomy:a technical trick to avoid loss of reductionof the opposite cortex. Knee Surg Sports Traumatol Arthrosc 2005; 13:19–22.  Back to cited text no. 25
Esenkaya I, Elmali N. Proximal tibia medial open-wedge osteotomy using plates with wedges: early results in 58 cases. Knee Surg Sports Traumatol Arthrosc 2006; 14:955–961.  Back to cited text no. 26
Niemeyer P, Koestler W, Kaehny C, Kreuz PC, Brooks CJ, Strohm PC et al. Arthroscopy: two-year results of open-wedge high tibial osteotomy with fixation by medial plate fixator for medial compartment arthritis with varus malalignment of the knee. J Arthrosc Relat Surg 2008; 24:796–804.  Back to cited text no. 27
Puddu G, Franco V, Cipolla M. Opening wedge osteotomy proximal tibia and distal femur. In: Jackson DW, editor. Master techniques in orthopaedic surgery: reconstructive knee surgery. 2n ed. Philadelphia, PA: Lippincott Williams & Wilkins 2002. pp. 375–390.  Back to cited text no. 28
Amendola A, Fowler PJ, Litchfield R. Opening-wedge high tibial osteotomy using a novel technique: early results and complications. J Knee Surg 2004; 17:164–169.  Back to cited text no. 29
Wright JM, Heavrin B, Begg M, Sakyrd G, Sterett W. Observations on patellar height following opening wedge proximal tibial osteotomy. Am J Knee Surg 2001; 14:163–173.  Back to cited text no. 30
Hernigou P. A 20-year follow-up study of internal gonarthrosis after tibial valgus osteotomy. Single versus repeated osteotomy. Rev Chir Orthop 1996; 82:241–250.  Back to cited text no. 31
Mertl P. Ostéotomie de valgisation par fermeture latérale. Rev Chir Orthop 2007; 93(Suppl 6):171–172.  Back to cited text no. 32
Bonnevialle P, Abid A, Mansat P, Verhaeghe L, Clement D, Mansat M. Tibial valgus osteotomy using a tricalcium phosphate medial wedge: a minimally invasive technique. Rev Chir Orthop 2002; 88:486–492.  Back to cited text no. 33
Goutallier D, Julieron A, Hernigou P. Cement wedge replacing iliac graft in tibial wedge osteotomy. Rev Chir Orthop 1992; 78:138–144.  Back to cited text no. 34
Koshino T, Tomihisa T, Murase T. Medial opening wedge high tibia osteotomy with use of porous hydroxyapatite to treat medial compartment osteoarthritis of the knee. J Bone Joint Surg (Am) 2003; 85-A:78–85.  Back to cited text no. 35
Levai JP, Bringer O, Descamps S, Boisgard S. Xenograft-related complications after filling valgus open wedge tibial osteotomy defects. Rev Chir Orthop 2003; 89:707–711.  Back to cited text no. 36


  [Figure 1], [Figure 2]

  [Table 1], [Table 2], [Table 3], [Table 4], [Table 5], [Table 6], [Table 7], [Table 8], [Table 9]


Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
Access Statistics
Email Alert *
Add to My List *
* Registration required (free)

  In this article
Patients and methods
Article Figures
Article Tables

 Article Access Statistics
    PDF Downloaded57    
    Comments [Add]    

Recommend this journal