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ORIGINAL ARTICLE
Year : 2017  |  Volume : 52  |  Issue : 2  |  Page : 158-164

Evaluation of the efficacy of autologous platelet-rich plasma injection versus local corticosteroid injection for the treatment of lateral epicondylitis


Orthopaedic Department, Faculty of Medicine, Menoufia University, Menoufia Governorate, Egypt

Correspondence Address:
Osama Gamal
Orthopaedic Department, Faculty of Medicine, Menoufia University, Gamal Abdel Nasser Street, Shebin El-Kom, Menoufia Governorate, 32511
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/eoj.eoj_42_17

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Background Local corticosteroid injection is a common treatment procedure for lateral epicondylitis. No statistically important or clinically better results favoring steroid injections were found in recent studies. Platelet-rich plasma (PRP) has shown a broad stimulating effect for repair and is used widely in different sports injuries. This study was performed to evaluate the effectiveness of local injection of autologous PRP versus corticosteroid to treat lateral epicondylitis. Patients and methods This prospective, randomized study included 40 patients with lateral epicondylitis: 20 in group A received 2 ml PRP and 20 in group B received 2 ml local corticosteroid. The final results were measured using the visual analog scale (VAS) for pain and Nirschl staging. The follow-up was continued for 6 months, with assessment at the 1st, 4th, 12th weeks and 6th months. Results The group B showed a significant pain improvement compared with group A in both VAS and Nirschl stage at the first and fourth weeks follow-up visits. At the 12th week visit, the VAS and Nirschl scores were significantly better in group A. At the sixth month follow-up, group A showed a statistically significant decrease in pain in comparison to group B (VAS P=0.001 and Nirschl P=0.002). At the 6-month final follow-up, nine (45%) patients in group B and 18 (90%) patients in group A were completely relieved of pain (P=0.007). Conclusion Autologous PRP is an effective treatment modality compared with corticosteroid injection, with less side effects and recurrence rate.


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